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Spermatogenesis

 Physiology of the male reproductive system

Spermatogenesis

I). Spermatogenesis

1). walls of the seminiferous tubes continuously dividing

2). The outer layer of cells divide into:

Basement membrane cells

Primary spermatocytes

 

Spermatogenesis

   Meiosis I results in

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spermatocyte         spermatocyte

 Meiosis II results in

arrow            arrow            arrow            arrow

Spermatid     Spermatid   Spermatid    Spermatid

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each spermatid now most undergo

Spermiogenesis

(development of motility)

II). Spermiogenesis

        A).  Sperm learn to swim 

Development of Sperm

B).  Regions of the sperm

1). Genetic Region: Head

acrosome a lysosome-like structure

2). Metabolic Region: Midpiece

Contains mitochondria

3). Locomotor: Tail

III). Sustentacular Cells

A). From Blood-Testes Barrier

Prevents the antigen from the sperm entering the blood stream

B). Move the sperm into the lumen

C). Supply transport medium

IV). How long does Spermatogenesis take?

 

 

V). Hormonal Control of Spermatogenesis and Testosterone Production

(Brain-Testicular Axis)

Brain-Testicula Axis

A).  Mechanism

1). Hypothalamus

(GnRH)

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2) Anterior Pituitary 

 (LH)          (FSH)

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3). Testes

i). LH

Testosterone (Androgen)Þ

enlargement of the testes
secondary sex characteristics
deepening voice
thickening skin
enlargement of the muscles

ii). FSH

 bind testosterone Þ

stimulating spermatogenesis

 

B). Feedback mechanisms

1). Testosterone inhibits GnRH

2). Testosterone inhibits FSH & LH

3).  Inhibin inhibits FSH and GnRH